Immunogenic hotspots in the spacer domain of ADAMTS13 in immune‐mediated thrombotic thrombocytopenic purpura

Author:

Velásquez Pereira Leydi Carolina1ORCID,Roose Elien1,Graça Nuno A. G.23,Sinkovits György4,Kangro Kadri1ORCID,Joly Bérangère S.5,Tellier Edwige67,Kaplanski Gilles6,Falter Tanja89,Von Auer Charis910,Rossmann Heidi89ORCID,Feys Hendrik B.1112,Reti Marienn13,Prohászka Zoltán4,Lämmle Bernhard91415ORCID,Voorberg Jan2,Coppo Paul1617,Veyradier Agnès5ORCID,De Meyer Simon F.1,Männik Andres3,Vanhoorelbeke Karen1

Affiliation:

1. Laboratory for Thrombosis Research IRF Life Sciences KU Leuven Campus Kulak Kortrijk Kortrijk Belgium

2. Department of Molecular and Cellular Hemostasis Sanquin Research and Landsteiner Laboratory Academic Medical Center University of Amsterdam Amsterdam the Netherlands

3. Icosagen Cell Factory OÜ Kambia vald, Tartumaa Estonia

4. Department of Internal Medicine and Hematology, and Research Group of Immunology and Hematology Hungarian Academy of Sciences and Semmelweis University Budapest Hungary

5. Service d’Hématologie biologique Hôpital Lariboisière Assistance Publique‐Hôpitaux de Paris and EA3518 Institut de Recherche Saint Louis Université de Paris Paris France

6. INSERM INRAE C2VN Aix‐Marseille Univ Marseille France

7. APHM INSERM C2VN CHU Conception Service de Médecine Interne et Immunologie Clinique Aix‐Marseille Univ Marseille France

8. Institute of Clinical Chemistry and Laboratory Medicine University Medical Center Johannes Gutenberg University Mainz Germany

9. Center for Thrombosis and Hemostasis University Medical Center of the Johannes Gutenberg University Mainz Germany

10. Department of Hematology, Oncology and Pneumology University Medical Center of the Johannes Gutenberg University Mainz Germany

11. Transfusion Research Center Belgian Red Cross‐Flanders Ghent Belgium

12. Faculty of Medicine and Health Sciences Ghent University Ghent Belgium

13. Department of Haematology and Stem Cell Transplantation Central Hospital of Southern Pest National Institute of Haematology and Infectious Diseases Budapest Hungary

14. Department of Hematology and Central Hematology Laboratory, Inselspital Bern University Hospital University of Bern Bern Switzerland

15. Haemostasis Research Unit University College London London UK

16. Service d'hématologie Hôpital Saint‐Antoine Assistance Publique ‐ Hôpitaux de Paris Paris France

17. Université Sorbonne Paris Cité Paris France

Funder

H2020 Marie Skłodowska-Curie Actions

Publisher

Wiley

Subject

Hematology

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