Critical stoichiometric ratio of CD4+ CD25+ FoxP3+regulatory T cells and CD4+ CD25−responder T cells influence immunosuppression in patients with B-cell acute lymphoblastic leukaemia

Author:

Bhattacharya Kaushik1,Chandra Sarmila2,Mandal Chitra1

Affiliation:

1. Cancer Biology and Inflammatory Disorder Division; Council of Scientific and Industrial Research - Indian Institute of Chemical Biology; Jadavpur Kolkata India

2. Park Clinic; Kolkata India

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference56 articles.

1. Naturally-occurring CD4+ CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance;Piccirillo;Semin Immunol,2004

2. Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications;André;Am J Pathol,2009

3. ICOS mediates the generation and function of CD4+ CD25+ Foxp3+  regulatory T cells conveying respiratory tolerance;Busse;J Immunol,2012

4. Control of regulatory T cell lineage commitment and maintenance;Josefowicz;Immunity,2009

5. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol,1995

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