Expression of the oncoprotein gankyrin and phosphorylated retinoblastoma protein in human testis and testicular germ cell tumor
Author:
Affiliation:
1. Department of Urology; University of Tsukuba; Tsukuba Japan
2. Department of Pathology; University of Tsukuba Hospital; Tsukuba Japan
3. Department of Clinical Molecular Biology; Graduate School of Medicine; Kyoto University; Kyoto Japan
Publisher
Wiley
Subject
Urology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/iju.12484/fullpdf
Reference17 articles.
1. Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas;Higashitsuji;Nat. Med.,2000
2. The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation;Higashitsuji;Cell Cycle,2005
3. Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells;Qiu;Oncogene,2008
4. Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance;Ortiz;Int. J. Cancer,2008
5. Gankyrin promotes the proliferation of human pancreatic cancer;Meng;Cancer Lett.,2010
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3. The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells;BMC Cancer;2019-11-19
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