Differential Effects of Antiepileptic Drugs on Focal Seizures in the Intrahippocampal Kainate Mouse Model of Mesial Temporal Lobe Epilepsy

Author:

Duveau Venceslas1,Pouyatos Benoît1,Bressand Karine1,Bouyssières Céline1,Chabrol Tanguy23,Roche Yann1,Depaulis Antoine234,Roucard Corinne1

Affiliation:

1. SynapCell SAS; La Tronche France

2. INSERM; U836; Grenoble France

3. University Grenoble Alpes; Grenoble Institut des Neurosciences; Grenoble France

4. CHU de Grenoble; Hôpital Michallon; Grenoble France

Funder

Ligue Française Contre l'Epilepsie

La Métro

Federación Española de Enfermedades Raras

Région Rhône-Alpes

INSERM

Pfizer

Publisher

Wiley

Subject

Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology

Reference31 articles.

1. Drug-resistant epilepsy;Kwan;N Engl J Med,2011

2. Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy;Riban;Neuroscience,2002

3. On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy;Krook-Magnuson;Nat Commun,2013

4. The temporopolar cortex plays a pivotal role in temporal lobe seizures;Chabardès;Brain,2005

5. Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice;Klein;Neuropharmacology,2014

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