Evaluation of “Test to Return” after COVID‐19 Diagnosis in a Massachusetts Public School District

Author:

Nelson Sandra B.1ORCID,Brenner Isaac Ravi2,Homan Elizabeth3,Lee Sarah Bott3,Bongiorno Christine4,Pollock Nira R.5,Ciaranello Andrea6

Affiliation:

1. Division of Infectious Diseases Massachusetts General Hospital, Boston, MA; Harvard Medical School Boston MA

2. Medical Practice Evaluation Center Massachusetts General Hospital Boston MA

3. Arlington Public Schools Arlington MA

4. Department of Health and Human Services Arlington MA

5. Harvard Medical School, Boston, MA; Department of Laboratory Medicine Boston Children's Hospital Boston MA

6. Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Medical Practice Evaluation Center Massachusetts General Hospital Boston MA

Abstract

ABSTRACTBACKGROUNDPer Centers for Disease Control and Prevention guidance, students with COVID‐19 may end isolation after 5 days if symptoms are improving; some individuals may still be contagious. Rapid antigen testing identifies possibly infectious virus. We report on a test‐to‐return (TTR) program in a Massachusetts school district to inform policy decisions about return to school after COVID‐19.METHODSDuring the 2021‐2022 Omicron BA.1 surge, students with COVID‐19 could return on day 6‐10 if they met symptom criteria and had a negative rapid test; students with positive rapid tests and those who declined TTR remained isolated until day 11. TTR positivity rates were compared by grade level, vaccination status, symptom status, and day of infection.RESULTS31.4% of students had a positive TTR rapid test; there were no differences by grade or vaccination status. Ever‐symptomatic students were more likely to have a positive rapid test (75/174 [43.1%] vs 18/104 [17.3%]). For ever‐symptomatic students, TTR positivity decreased by day of infection.CONCLUSIONSA substantial proportion of students may still be contagious 6 days after onset of COVID‐19 infection. TTR programs may increase or reduce missed school days, depending on when return is otherwise allowed (day 6 or 11). The impact of TTR programs on school‐associated transmission remains unknown.

Publisher

Wiley

Subject

Public Health, Environmental and Occupational Health,Philosophy,Education

Reference21 articles.

1. Centers for Disease Control and Prevention.CDC Updates and Shortens Recommended Isolation and Quarantine Period for General Population. December 27 2021. Available at:https://www.cdc.gov/media/releases/2021/s1227‐isolation‐quarantine‐guidance.html. Accessed February 9 2022.

2. Viral Dynamics of Omicron and Delta Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants With Implications for Timing of Release from Isolation: A Longitudinal Cohort Study

3. Viral Cultures for Coronavirus Disease 2019 Infectivity Assessment: A Systematic Review

4. Antigen-Based Testing but Not Real-Time Polymerase Chain Reaction Correlates With Severe Acute Respiratory Syndrome Coronavirus 2 Viral Culture

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