Hepatic stellate cells that coexpress LRAT and CRBP-1 partially contribute to portal fibrogenesis in patients with human viral hepatitis

Author:

Nagatsuma Keisuke12,Hano Hiroshi2,Murakami Kazuhiro3,Shindo Daisuke4,Matsumoto Yoshihiro1,Mitobe Jimi12,Tanaka Ken1,Saito Masaya5,Maehashi Haruka4,Owada Mamiko2,Ikegami Masahiro2,Tsubota Akihito6,Ohkusa Toshifumi7,Aizawa Yoshio8,Takagi Ichiro1,Tajiri Hisao1,Matsuura Tomokazu14

Affiliation:

1. Division of Gastroenterology and Hepatology; Department of Internal Medicine; The Jikei University School of Medicine; Tokyo Japan

2. Department of Pathology; The Jikei University School of Medicine; Tokyo Japan

3. Division of Clinical Pathology; Tohoku Welfare Pension Hospital; Sendai Japan

4. Department of Laboratory Medicine; The Jikei University School of Medicine; Tokyo Japan

5. Kaijo Bldg. Clinic; Tokyo Japan

6. Institute of Clinical Medicine and Research (ICMR); The Jikei University School of Medicine; Chiba Japan

7. Division of Gastroenterology and Hepatology, Kashiwa Hospital; The Jikei University School of Medicine; Chiba Japan

8. Division of Gastroenterology and Hepatology; Katsushika Medical Centre; The Jikei University School of Medicine; Tokyo Japan

Funder

High Technology Research Center

Grants-in-Aid for Scientific Research

Publisher

Wiley

Subject

Hepatology

Reference48 articles.

1. Liver fibrosis;Bataller;J Clin Invest,2005

2. Commitment of bone marrow cells to hepatic stellate cells in mouse;Baba;J Hepatol,2004

3. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis;Kisseleva;J Hepatol,2006

4. A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis;Forbes;Gastroenterology,2004

5. The bone marrow functionally contributes to liver fibrosis;Russo;Gastroenterology,2006

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