If not angioedema, what is it? Diagnostic approach to facial edema

Author:

Velasco‐Amador Juan Pablo1,Prados‐Carmona Álvaro1ORCID,Navarro‐Triviño Francisco José2ORCID

Affiliation:

1. Servicio de Dermatología Hospital Universitario San Cecilio Granada Spain

2. Departamento de Eczema de Contacto e Inmunoalergia Servicio de Dermatología Médico‐Quirúrgica y Venereología Hospital Universitario San Cecilio Granada Spain

Abstract

SummaryFacial edema is a relatively frequent clinical presentation encountered in patients seen in allergology and dermatology clinics. The differential diagnosis is broad, and sometimes the definitive diagnosis can be a challenge for the clinician. Facial angioedema itself encompasses different etiopathologies (histaminergic, bradykinergic, etc.) that must be distinguished from other causes of facial edema, such as allergic contact dermatitis, granulomatous conditions, inflammatory causes, infections, neoplasms or paraneoplastic syndromes, autoimmune diseases, among other entities hereby referred as miscellanea. A proper diagnostic approach is essential to order the appropriate tests, as well as to prescribe a targeted treatment. This review focuses on entities that present with facial edema and summarize their characteristic clinical features.

Publisher

Wiley

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