IgG4 drives M2a macrophages to a regulatory M2b-like phenotype: potential implication in immune tolerance

Author:

Bianchini Rodolfo1ORCID,Roth-Walter Franziska1ORCID,Ohradanova-Repic Anna2ORCID,Flicker Sabine3ORCID,Hufnagl Karin1ORCID,Fischer Michael Bernhard45ORCID,Stockinger Hannes3ORCID,Jensen-Jarolim Erika13ORCID

Affiliation:

1. Department of Comparative Medicine; The Interuniversity Messerli Research Institute; University of Veterinary Medicine Vienna; Medical University of Vienna; University Vienna; Vienna Austria

2. Institute for Hygiene and Applied Immunology; Center for Pathophysiology, Infectiology and Immunology; Medical University of Vienna; Vienna Austria

3. Institute of Pathophysiology and Allergy Research; Center for Pathophysiology, Infectiology and Immunology; Medical University of Vienna; Vienna Austria

4. Department of Blood Group Serology and Transfusion Medicine; Medical University Vienna; Vienna Austria

5. Department of Health Science and Biomedicine; Danube University Krems; Vienna Austria

Funder

Austrian Science Fund

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference39 articles.

1. Mechanisms of allergen-specific immunotherapy;Fujita;Clin Transl Allergy,2012

2. Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses;Bruhns;Blood,2009

3. The function of Fcgamma receptors in dendritic cells and macrophages;Guilliams;Nat Rev Immunol,2014

4. Understanding the Mysterious M2 macrophage through activation markers and effector mechanisms;Roszer;Mediators Inflamm,2015

5. Macrophage activation switching: an asset for the resolution of inflammation;Porcheray;Clin Exp Immunol,2005

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