PTH, vitamin D, and the FGF-23-klotho axis and heart: Going beyond the confines of nephrology

Author:

Navarro-García José Alberto1,Fernández-Velasco María2,Delgado Carmen3,Delgado Juan F.4,Kuro-o Makoto5,Ruilope Luis M.167ORCID,Ruiz-Hurtado Gema1

Affiliation:

1. Cardiorenal Translational Laboratory; Institute of Research i+12; Hospital Universitario de Octubre/CIBERCV; Madrid Spain

2. IdiPAZ Institute for Health Research/CIBERCV; Madrid Spain

3. Biomedical Research Institute Alberto Sols/CIBERCV; Madrid Spain

4. Cardiology Service; Hospital Universitario 12 de Octubre/CIBERCV; Madrid Spain

5. Division of Anti-aging Medicine; Center for Molecular Medicine; Jichi Medical University; Shimotsuke Tochigi Japan

6. Department of Preventive Medicine and Public Health; School of Medicine; Universidad Autónoma de Madrid; Madrid Spain

7. European University of Madrid; Madrid Spain

Funder

Instituto de Salud Carlos III

Ministerio de Economía y Competitividad

Fundación SENEFRO/Sociedad Española de Nefrología

Sociedad Española de Cardiología

Fundación Íñigo Álvarez de Toledo

CIBER de Enfermedades Cardiovasculares

Federación Española de Enfermedades Raras

Publisher

Wiley

Subject

Clinical Biochemistry,Biochemistry,General Medicine

Reference91 articles.

1. Novel mechanisms in the regulation of phosphorus homeostasis;Berndt;Physiology (Bethesda),2009

2. Phosphatonins and the regulation of phosphate homeostasis;Berndt;Annu Rev Physiol,2007

3. Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism;Kuro-o;Nat Rev Nephrol,2013

4. FGF23 induces left ventricular hypertrophy;Faul;J Clin Invest,2011

5. Elevated parathyroid hormone, but not vitamin D deficiency, is associated with increased risk of heart failure in older men with and without cardiovascular disease;Wannamethee;Circ Heart Fail,2014

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