First‐in‐human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G‐protein‐biased sphingosine‐1 phosphate receptor‐1 agonist for endothelial protection
Author:
Affiliation:
1. Sanofi R&D Chilly Mazarin France
2. Parexel International GmBH Berlin Germany
3. Sanofi R&D Montpellier France
4. Sanofi US Services Cambridge MA USA
5. Sanofi US Services Bridgewater NJ USA
Funder
Sanofi
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.14422
Reference33 articles.
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4. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
5. Gilenya (fingolimod) package insert. Basel Switzerland. Novartis pharmaceuticals2019.
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