A novel androgen signalling pathway uses dihydrotestosterone, but not testosterone, to activate the EGF receptor signalling cascade in prostate stromal cells
Author:
Affiliation:
1. Drug Discovery Biology; Monash Institute of Pharmaceutical Sciences; Monash University (Parkville Campus); Parkville; Vic.; Australia
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.12307/fullpdf
Reference43 articles.
1. The potent synthetic androgens, dimethandrolone (7alpha,11beta-dimethyl-19-nortestosterone) and 11betaβ-methyl-19-nortestosterone, do not require 5alpha-reduction to exert their maximal androgenic effects;Attardi;J Steroid Biochem Mol Biol,2010
2. The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye;Baker;Cell,2001
3. Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells;Bakin;Cancer Res,2003
4. Cytoskeletal association of epidermal growth factor receptor and associated signaling proteins is regulated by cell density in IEC-6 intestinal cells;Bedrin;J Cell Physiol,1997
5. Testosterone induces Ca2+ influx via non-genomic surface receptors in activated T cells;Benten;FEBS Lett,1997
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The testosterone paradox of advanced prostate cancer: mechanistic insights and clinical implications;Nature Reviews Urology;2022-12-21
2. Dihydrotestosterone regulation of cyclooxygenase-2 expression in bovine endometrial epithelium cells by androgen receptor mediated EGFR/PI3K/Akt pathway;The Journal of Steroid Biochemistry and Molecular Biology;2021-11
3. Oral exposure to low-dose bisphenol A induces hyperplasia of dorsolateral prostate and upregulates EGFR expression in adult Sprague-Dawley rats;Toxicology and Industrial Health;2019-10
4. “Put It in Your Shoe It Will Make You Limp”: British Men’s Online Responses to a Male Pill;The Journal of Men’s Studies;2018-04-03
5. The Response of Prostate Smooth Muscle Cells to Testosterone Is Determined by the Subcellular Distribution of the Androgen Receptor;Endocrinology;2017-11-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3