Affiliation:
1. Department of Obstetrics and Gynecology Division of Perinatology Turkish Ministry of Health Ankara City Hospital Ankara Turkey
2. University of Health Sciences, Department of Obstetrics and Gynecology, Division of Perinatology Turkish Ministry of Health Ankara City Hospital Ankara Turkey
Abstract
AbstractObjectiveTo compare the fetal pulmonary artery Doppler indices of pregnant women with autoimmune diseases such as systemic lupus erythematosus (SLE), Sjögren's syndrome (SS), and antiphospholipid syndrome (APS) with healthy pregnant women.MethodsThirty‐nine pregnancies were included in the case group, 19 of them SLE, 12 with SS, and eight with APS. The gestational age‐matched 54 healthy pregnant women were included in the control group. Peak systolic velocity, time‐averaged velocity, systolic/diastolic ratio, pulsatility index, resistance index, acceleration time (AT), ejection time (ET), and AT/ET ratio were obtained from pulmonary artery waveform by using spectral Doppler ultrasound.ResultsSignificantly shorter AT and lower AT/ET ratio were detected in the case group (p = < .001, p = < .001, respectively). The shortening of AT and decreasing of the AT/ET ratio were more predominant in the APS group. However, there was no significant difference between the SLE, SS, and APS groups in fetal pulmonary artery Doppler indices. Also, a moderate correlation was found between maternal disease duration (years) and fetal pulmonary artery AT (r = −.516, p = .001) and AT/ET ratio (r = −.558, p = < .001).ConclusionFetal pulmonary artery Doppler indices may be affected in maternal autoimmune diseases. Further studies are needed to evaluate fetal pulmonary Doppler indices such as AT and AT/ET ratio to predict neonatal respiratory morbidity and lung maturation in pregnant women with SLE, SS, and APS.
Subject
Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging
Cited by
1 articles.
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