Affiliation:
1. Nursing Department The First People's Hospital of Nanyang City Nanyang China
2. Surgical Department The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture Enshi China
3. Nuclear Medicine Department Shenzhen Sun Yat Sen University Affiliated Seventh Hospital Shenzhen China
4. Medicine Department Yangtze University College of Arts and Sciences Jingzhou China
5. General Surgery Department Liyuan Hospital Affiliated To Tongji Medical College Huazhong University Of Science And Technology Wuhan China
Abstract
AbstractThis meta‐analysis evaluates the efficacy of silver alginate dressings (SAD) compared to standard gauze (SG) in enhancing wound healing and reducing scar formation post‐mastectomy in patients with triple‐negative breast cancer. From an initial pool of 1245 articles, five studies met the inclusion criteria. The analysis revealed that SAD significantly improve early wound healing 1 week post‐mastectomy, as indicated by lower Redness, Edema, Ecchymosis, Discharge, and Approximation (REEDA) scales (I2 = 85%; Random: SMD: −7.08, 95% CI: −8.26 to −5.98, p < 0.01), compared to SG. Additionally, long‐term scar outcomes measured by the Manchester Scar Scale (MSS) 5 months post‐mastectomy showed a notable reduction in scar formation (I2 = 95%; Random: SMD: −12.97, 95% CI: −16.20 to −9.75, p < 0.01)) in the silver alginate group. The findings support the use of SAD in post‐mastectomy care for triple‐negative breast cancer patients but highlight the need for further research on long‐term safety and cost‐effectiveness.