Population pharmacokinetics analysis of guselkumab in healthy subjects and patients with psoriatic arthritis, plaque psoriasis and palmoplantar pustulosis-Reference-Cited by-同舟云学术

Population pharmacokinetics analysis of guselkumab in healthy subjects and patients with psoriatic arthritis, plaque psoriasis and palmoplantar pustulosis

Published:2022-05-13 Issue:10 Volume:88 Page:4481-4493
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Brit J Clinical Pharma

Author:

Tran Lana¹^ORCID,Yao Zhenling¹,Xu Zhenhua¹,Vermeulen An²

Affiliation:

1. Clinical Pharmacology and Pharmacometrics Janssen Research & Development, LLC Spring House PA USA

2. Clinical Pharmacology and Pharmacometrics Janssen Research & Development, a division of Janssen Pharmaceutica NV Beerse Belgium

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.15364

Reference37 articles.

1. Population Pharmacokinetic Modeling of Guselkumab, a Human IgG1λ Monoclonal Antibody Targeting IL‐23, in Patients with Moderate to Severe Plaque Psoriasis

2. IL-23 Drives Pathogenic IL-17-Producing CD8+ T Cells

3. Cytokine Requirements for the Differentiation and Expansion of IL-17A– and IL-22–Producing Human Vγ2Vδ2 T Cells

4. IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

5. Composition of Innate Lymphoid Cell Subsets in the Human Skin: Enrichment of NCR + ILC3 in Lesional Skin and Blood of Psoriasis Patients

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