Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years

Author:

Borobia Alberto M.1,Dapia Irene23,Tong Hoi Y.1,Arias Pedro23,Muñoz Mario1,Tenorio Jair23,Hernández Rafael1,García García Irene1,Gordo Gema23,Ramírez Elena1,Frías Jesús1,Lapunzina Pablo23,Carcas Antonio J.1

Affiliation:

1. Clinical Pharmacology Department; IdiPAZ, La Paz University Hospital, School of Medicine; Autonomous University of Madrid; Madrid Spain

2. Medical and Molecular Genetics Institute (INGEMM); La Paz University Hospital; Madrid Spain

3. Center for Biomedical Network Research on Rare Diseases (CIBERER); ISCIII; Madrid Spain

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference23 articles.

1. International Conference on Harmonisation; guidance on specifications: test procedures and acceptance criteria for biotechnological/biological products. Notice. Food and Drug Administration, HHS;Fed. Regist.,1999

2. Pharmacogenomic information in drug labels: European Medicines Agency perspective;Ehmann;Pharmacogenomics J.,2015

3. Personalizing medicine with clinical pharmacogenetics;Scott;Genet. Med.,2011

4. Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol;Bielinski;Mayo Clin. Proc.,2014

5. Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain;Agundez;Front. Genet.,2012

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