Cyclin D1, p16INK4Aand p27Kip1in pancreatic adenocarcinoma: assessing prognostic implications through quantitative image analysis

Author:

Georgiadou Despoina1,Sergentanis Theodoros N.2,Sakellariou Stratigoula3,Filippakis George M.4,Zagouri Flora4,Vlachodimitropoulos Dimitris5,Psaltopoulou Theodora2,Lazaris Andreas C.3,Patsouris Efstratios3,Zografos George C.4

Affiliation:

1. 3rd Surgical Clinic of George Gennimatas General Hospital; Mesogeion Ave 154 Athens 156 69 Greece

2. Department of Hygiene; Epidemiology and Medical Statistics; School of Medicine; University of Athens; Athens Greece

3. 1st Department of Pathology; National and Kapodistrian University of Athens; Athens Greece

4. 1st Department of Propaedeutic Surgery; Hippokratio Hospital; Athens Greece

5. Department of Forensic Pathology and Toxicology; Medical School; University of Athens; Athens Greece

Funder

Alexandros Onassis Foundation

Publisher

Wiley

Subject

Microbiology (medical),General Medicine,Immunology and Allergy,Pathology and Forensic Medicine

Reference51 articles.

1. Epidemiology of pancreatic cancer: an overview;Raimondi;Nat Rev Gastroenterol Hepatol,2009

2. G1 cell-cycle control and cancer;Massague;Nature,2004

3. Cyclin D as a therapeutic target in cancer;Musgrove;Nat Rev Cancer,2011

4. Differential expressions of cyclin D1 associated with better prognosis of cancers of ampulla of Vater;Chang;World J Surg,2007

5. Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis;Gansauge;Cancer Res,1997

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