A conversation on allergy: recognizing the past and looking to the future

Author:

Melén Erik1,Lambrecht Bart N2,Lloyd Clare M3,Rothenberg Marc E4,Kabashima Kenji5,Luciani Fabio6,Coquet Jonathan M7,Ober Carole8,Nawijn Martijn C9,Platts‐Mills Thomas10,von Mutius Erika11

Affiliation:

1. Department of Clinical Sciences and Education Karolinska Institutet, Södersjukhuset Stockholm Sweden

2. Laboratory of Mucosal Immunology VIB‐UGent Center for Inflammation Research, Ghent University Ghent Belgium

3. National Heart & Lung Institute, Faculty of Medicine Imperial College London UK

4. Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine Cincinnati OH USA

5. Department of Dermatology Kyoto University Graduate School of Medicine Kyoto Japan

6. UNSW Sydney, School of Medical Sciences Kirby Institute Sydney NSW Australia

7. Leo Foundation Skin Immunology Research Center Department of Immunology and Microbiology, University of Copenhagen Copenhagen Denmark

8. Department of Human Genetics University of Chicago Chicago IL USA

9. University of Groningen, University Medical Center Groningen, Department of Pathology & Medical Biology, GRIAC Research Institute Groningen The Netherlands

10. School of Medicine University of Virginia Charlottesville VA USA

11. Ludwig Maximilians University Munich, Institute of Asthma and Allergy Prevention at Helmholtz Centre Munich Munich Germany

Abstract

AbstractAllergy is an ever‐evolving group of disorders, which includes asthma, atopic dermatitis, rhinitis and food allergies and that currently affects over 1 billion people worldwide. This group of disorders has exploded in incidence since around the start of the 20th century, implying that genetics is not solely responsible for its development but that environmental factors have an important role. Here, Fabio Luciani and Jonathan Coquet, in their role as editors at Immunology & Cell Biology, asked nine prominent researchers in the field of allergy to define the term ‘allergy’, discuss the role of genetics and the environment, nominate the most important discoveries of the past decade and describe the best strategies to combat allergy at the population level going forward.

Publisher

Wiley

Subject

Cell Biology,Immunology,Immunology and Allergy

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