Functional analysis of drug resistance-associated mutations in theTrypanosoma bruceiadenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein-Reference-Cited by-同舟云学术

Functional analysis of drug resistance-associated mutations in theTrypanosoma bruceiadenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein

Published:2015-03-21 Issue:4 Volume:96 Page:887-900
ISSN:0950-382X
Container-title:Molecular Microbiology
language:en
Short-container-title:Molecular Microbiology

Author:

Munday Jane C.¹²,Tagoe Daniel N. A.¹³,Eze Anthonius A.¹⁴,Krezdorn Jessica A. M.¹,Rojas López Karla E.¹,Alkhaldi Abdulsalam A. M.¹⁵,McDonald Fiona¹,Still Jennifer¹,Alzahrani Khalid J.¹⁶,Settimo Luca¹⁷,De Koning Harry P.¹

Affiliation:

1. Institute of Infection, Immunity and Inflammation; College of Medical, Veterinary and Life Sciences; University of Glasgow; Glasgow G12 8TA UK

2. Wellcome Trust Centre for Molecular Parasitology; University of Glasgow; Glasgow UK

3. Department of Laboratory Technology; University of Cape Coast; Cape Coast Ghana

4. Department of Medical Biochemistry; College of Medicine; University of Nigeria; Enugu Campus Enugu Nigeria

5. Department of Biology; College of Science; Aljouf University; Sakaka Saudi Arabia

6. Faculty of Medical Sciences; Taif University; Taif Saudi Arabia

7. Department of Chemistry and Chemical Biology; 417 Egan Research Center; Northeastern University; 360 Huntington Avenue Boston MA 02115 USA

Funder

Medical Research Council

Publisher

Wiley

Subject

Molecular Biology,Microbiology

Reference66 articles.

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3. Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes;Baker;Proc Natl Acad Sci USA,2012

4. Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story;Baker;Trends Parasitol,2013

5. Drug resistance in human African trypanosomiasis;Barrett;Future Microbiol,2011

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