CD33 ‐targeting extracellular vesicles deliver antisense oligonucleotides against FLT3‐ITD and miR ‐125b for specific treatment of acute myeloid leukaemia

Author:

Chen Huan123ORCID,Jayasinghe Migara Kavishka12,Yeo Eric Yew Meng12,Wu Zhiyuan12,Pirisinu Marco3,Usman Waqas Muhammad3,Pham Thach Tuan12,Lim Kah Wai4,Tran Nhan Van4,Leung Anskar Y. H.5,Du Xin6,Zhang Qiaoxia6,Phan Anh Tuân4,Le Minh T. N.12ORCID

Affiliation:

1. Department of Pharmacology, Institute for Digital Medicine, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

2. Department of Surgery, Immunology Program, Cancer Program and Nanomedicine Translational Program, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

3. Department of Biomedical Sciences, Jockey Club College of Veterinary Medicine and Life Sciences City University of Hong Kong Kowloon Hong Kong SAR

4. Division of Physics & Applied Physics, School of Physical & Mathematical Sciences Nanyang Technological University Singapore Singapore

5. Department of Medicine, Li Ka Shing Faculty of Medicine, Queen Mary Hospital The University of Hong Kong Pok Fu Lam Hong Kong SAR

6. Department of Hematology and Shenzhen Bone Marrow Transplantation Public Service Platform, Shenzhen Second People's Hospital The First Affiliated Hospital of Shenzhen University, Shenzhen University School of Medicine Shenzhen China

Funder

National University of Singapore

Publisher

Wiley

Subject

Cell Biology,General Medicine

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