1. Asmuth DM , Olson RD , Hackett SP , Bryant AE , Tweten RK , Tso JY , Zollman T & Stevens DL (1995) Effects of Clostridium perfringens recombinant and crude phospholipase C and theta-toxin on rabbit hemodynamic parameters. J Infect Dis 172: 1317â1323.
2. Awad MM , Bryant AE , Stevens DL & Rood JI (1995) Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene. Mol Microbiol 15: 191â202.
3. Bryant AE & Stevens DL (1996) Phospholipase C and perfringolysin O from Clostridium perfringens upregulate endothelial cell-leukocyte adherence molecule 1 and intercellular leukocyte adherence molecule 1 expression and induce interleukin-8 synthesis in cultured human umbilical vein endothelial cells. Infect Immun 64: 358â362.
4. The Pathogenesis of Gas Gangrene
5. Bryant AE , Chen RY , Nagata Y , Wang Y , Lee CH , Finegold S , Guth PH & Stevens DL (2000a) Clostridial gas gangrene. II. Phospholipase C-induced activation of platelet gpIIbIIIa mediates vascular occlusion and myonecrosis in Clostridium perfringens gas gangrene. J Infect Dis 182: 808â815.