Multimerization of anti-(epidermal growth factor receptor) IgG fragments induces an antitumor effect: the case for humanized 528 scFv multimers
Author:
Affiliation:
1. Department of Biomolecular Engineering; Graduate School of Engineering, Tohoku University; Sendai Japan
2. Department of Pharmacology; Tohoku University School of Medicine; Sendai Japan
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12451/fullpdf
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4. Isolation of a human anti-epidermal growth factor receptor Fab antibody, EG-19-11, with subnanomolar affinity from naive immunoglobulin repertoires using a hierarchical antibody library system;Hur;Immunol Lett,2010
5. In vitro and in vivo anti-tumor activities of anti-EGFR single-chain variable fragment fused with recombinant gelonin toxin;Zhou;J Cancer Res Clin Oncol,2012
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