NAD(P)HXrepair deficiency causes central metabolic perturbations in yeast and human cells

Author:

Becker‐Kettern Julia1,Paczia Nicole1,Conrotte Jean‐François1,Zhu Chenchen2,Fiehn Oliver3,Jung Paul P.1,Steinmetz Lars M.245,Linster Carole L.1

Affiliation:

1. Luxembourg Centre for Systems Biomedicine University of Luxembourg Belvaux Luxembourg

2. European Molecular Biology Laboratory (EMBL) Genome Biology Unit Heidelberg Germany

3. NIH West Coast Metabolomics Center University of California Davis CA USA

4. Stanford Genome Technology Center Stanford University Palo Alto CA USA

5. Department of Genetics Stanford University School of Medicine CA USA

Funder

Fonds National de la Recherche Luxembourg

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference63 articles.

1. The action of glyceraldehyde‐3‐phosphate dehydrogenase on reduced diphosphopyridine nucleotide;Rafter GW;J Biological Chem,1954

2. Glyceraldehyde-3-phosphate dehydrogenase catalyzed hydration of the 5-6 double bond of reduced β-nicotinamide adenine dinucleotide (βNADH). Formation of β-6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide

3. Structure of the primary acid rearrangement product of reduced nicotinamide adenine dinucleotide (NADH)

4. Inhibition of NADP-dependent dehydrogenases by modified products of NADPH

5. Enzymatic conversion of a reduced diphosphopyridine nucleotide derivative to reduced diphosphopyridine nucleotide;Meinhart JO;J Biol Chem,1956

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