Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke

Author:

Karabiyik Cansu123,Fernandes Rui14,Figueiredo Francisco Rosário14,Socodato Renato12,Brakebusch Cord5,Lambertsen Kate Lykke367,Relvas João Bettencourt12,Santos Sofia Duque128ORCID

Affiliation:

1. i3S - Instituto de Investigação e Inovação em Saúde; Universidade do Porto; Porto Portugal

2. Glial Cell Biology; IBMC- Instituto de Biologia Molecular e Celular, Universidade do Porto; Porto Portugal

3. Department of Neurobiology Research, Institute of Molecular Medicine; University of Southern Denmark; Odense C Denmark

4. HEMS, IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto; Porto Portugal

5. Biotech Research and Innovation Center; University of Copenhagen; Denmark

6. Department of Neurology; Odense University Hospital; Odence C Denmark

7. BRIDGE - Brain Research - Inter-Disciplinary Guided Excellence, Department of Clinical Research, University of Southern Denmark, Odense; Denmark

8. INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto; Portugal.

Funder

Federación Española de Enfermedades Raras

Portuguese funds through Fundação para a Ciência e a Tecnologia - FCT

Programa Ciência - financiado pelo POPH - QREN - Tipologia 4.2

Fuel Cycle Technologies

Publisher

Wiley

Subject

Clinical Neurology,Pathology and Forensic Medicine,General Neuroscience

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