Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers

Author:

Dijkstra Francis M.12ORCID,Zuiker Rob G. J. A.12ORCID,Siebenga Pieter S.1ORCID,Leigh‐Pemberton Richard A.3,Sun Lei3,Manthis Joan D.3,de Kam Marieke L.1,Lin Richard3,von Moltke Lisa L.3,Rezendes David3,van Gerven Joop M. A.12

Affiliation:

1. Centre for Human Drug Research (CHDR) Leiden The Netherlands

2. Leiden University Medical Center Leiden The Netherlands

3. Alkermes, Inc. Waltham MA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference40 articles.

1. FDA.Guidance for Industry: Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers.https://www.fda.gov/media/72309/downloadPublished2005. Accessed January 28 2021.

2. Measuring blood–brain barrier penetration using the NeuroCart, a CNS test battery

3. Functional Measurements of Central Nervous System Drug Effects in Early Human Drug Development

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