Oral esomeprazole in Japanese pediatric patients with gastric acid-related disease: Safety, efficacy, and pharmacokinetics

Author:

Shimizu Toshiaki1ORCID,Nakayama Yoshiko2ORCID,Ishii Eizaburo3,Ida Shinobu4,Satou Tomoki5,Tokuhara Daisuke6ORCID,Arai Katsuhiro7,Nii Masahiro8,Rydholm Hans9,Yajima Toshitaka8,

Affiliation:

1. Department of Pediatrics and Adolescent Medicine; Juntendo University Graduate School of Medicine; Matsumoto Nagano Japan

2. Department of Pediatrics; Shinshu University School of Medicine; Matsumoto Nagano Japan

3. Department of Pediatrics; Nagano Prefectural Suzaka Hospital; Suzaka Nagano Japan

4. Department of Pediatric Gastroenterology; Nutrition and Endocrinology, Osaka Women's and Children's Hospital; Izumi Japan

5. Department of Pediatrics; Hiroshima City Funairi Citizens Hospital; Hiroshima Japan

6. Department of Pediatrics; Osaka City University Graduate School of Medicine; Abeno Tokyo Japan

7. Division of Gastroenterology; National Center for Child Health and Development; Setagaya Tokyo Japan

8. Research and Development; AstraZeneca; Kitaku Osaka Japan

9. Global Medicine Development; AstraZeneca Gothenburg; Mölndal Sweden

Funder

AstraZeneca

Publisher

Wiley

Subject

Pediatrics, Perinatology and Child Health

Reference23 articles.

1. The Montreal definition and classification of gastroesophageal reflux disease: A global evidence-based consensus;Vakil;Am. J. Gastroenterol.,2006

2. World Gastroenterology Organisation World Gastroenterology Organisation Global Guidelines: GERD. Global Perspective on Gastroesophageal Reflux Disease 2015 http://www.worldgastroenterology.org/UserFiles/file/guidelines/gastroesophagel-reflux-disease-english-2015.pdf

3. Prevalence of symptoms of gastroesophageal reflux during childhood: A pediatric practice-based survey. Pediatric Practice Research Group;Nelson;Arch. Pediatr. Adolesc. Med.,2000

4. Prevalence of gastroesophageal reflux disease in children, adults, and elderly in the same community;Okimoto;J. Gastroenterol. Hepatol.,2015

5. A global, evidence-based consensus on the definition of gastroesophageal reflux disease in the pediatric population;Sherman;Am. J. Gastroenterol.,2009

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1. Gastroesophageal Reflux;Textbook of Pediatric Gastroenterology, Hepatology and Nutrition;2021-11-25

2. Adverse reactions related to proton pump inhibitors in pediatric population: an analysis of spontaneous reporting data;Expert Opinion on Drug Safety;2021-09-20

3. Proton pump inhibitors: Oral treatment of pediatric disorders;Pediatrics International;2019-01

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