Activation of the phosphatidylinositol 3-kinase pathway plays important roles in reduction of cerebral infarction by cilnidipine

Author:

Son Jeong-Woo1,Choi Hojin2,Yoo Arum2,Park Hyun-Hee2,Kim Young-Seo2,Lee Kyu-Yong2,Lee Young Joo2,Koh Seong-Ho12

Affiliation:

1. Department of Translational Medicine; Hanyang University Graduate School of Biomedical Science & Engineering; Seoul Korea

2. Department of Neurology; Hanyang University College of Medicine; Seoul Korea

Funder

Korea Research Foundation

Ministry of Education, Science and Technology

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference27 articles.

1. The phosphoinositide 3-kinase pathway;Cantley;Science,2002

2. Phosphoinositide 3-kinase signalling pathways;Cantrell;J. Cell Sci.,2001

3. Effect of nimodipine on final infarct volume after acute ischemic stroke;Fogelholm;Cerebrovasc. Dis.,2000

4. A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation;Frame;Mol. Cell,2001

5. A controlled trial of nimodipine in acute ischemic stroke;Gelmers;N. Engl. J. Med.,1988

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