Sulfate conjugation may be the key to hepatotoxicity in paracetamol overdose-Reference-Cited by-同舟云学术

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Sulfate conjugation may be the key to hepatotoxicity in paracetamol overdose

Published:2020-12-07 Issue:5 Volume:87 Page:2392-2396
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Brit Jnl Clinical Pharma

Author:

Li Jingyun¹^ORCID,Chiew Angela L.²³⁴^ORCID,Isbister Geoffrey K.⁴⁵^ORCID,Duffull Stephen B.¹

Affiliation:

1. School of Pharmacy University of Otago Dunedin New Zealand

2. Emergency Department and Clinical Toxicology Prince of Wales Hospital and Community Health Services Randwick Australia

3. Department of Pharmacology, School of Medical Sciences University of Sydney Sydney Australia

4. NSW Poisons Information Centre Children's Hospital at Westmead Westmead Australia

5. Clinical Toxicology Research Group University of Newcastle Newcastle Australia

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.14642

Reference21 articles.

1. Acute liver failure

2. Kinetics and metabolism of paracetamol and phenacetin.

3. Drug conjugation in clinical toxicology

4. The role of drug metabolizing enzymes in clearance

5. The importance of 3‘‐phosphoadenosine 5‘‐phosphosulfate (PAPS) in the regulation of sulfation

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