1. Department of Statistics; Purdue University; 250 N. University Street, West Lafayette, Indiana 47907 U.S.A.
2. Department of Bioinformatics and Computational Biology; The University of Texas MD Anderson Cancer Center; 1400 Pressler Dr., Houston, Texas 77030 U.S.A.
3. Department of Biostatistics; The University of Texas MD Anderson Cancer Center; 1400 Pressler Dr., Houston,Texas 77030 U.S.A.