Geranylgeranylacetone promotes human osteosarcoma cell apoptosis by inducing the degradation of PRMT1 through the E3 ubiquitin ligase CHIP
Author:
Affiliation:
1. Department of Pathology The Third Affiliated Hospital of Southern Medical University Guangzhou China
2. Department of Pathophysiology School of Medicine Jinan University Guangzhou China
Funder
Fundamental Research Funds for the Central Universities
Publisher
Wiley
Subject
Cell Biology,Molecular Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.16725
Reference33 articles.
1. Primary Osteosarcoma in the Elderly Revisited: Current Concepts in Diagnosis and Treatment
2. Osteosarcoma: Molecular Pathogenesis and iPSC Modeling
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5. Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats;Murakami M;Arzneimittelforschung,1981
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1. Knockdown of PRMT1 suppresses the malignant biological behavior of osteosarcoma cells and increases cisplatin sensitivity via c‐Myc‐mediated BCAT1 downregulation;Journal of Biochemical and Molecular Toxicology;2023-09-13
2. STUB1/CHIP: New insights in cancer and immunity;Biomedicine & Pharmacotherapy;2023-09
3. GGA (geranylgeranylacetone) ameliorates bleomycin-induced lung inflammation and pulmonary fibrosis by inhibiting apoptosis and oxidative stress;Molecular Biology Reports;2023-07-07
4. Cellular functions and molecular mechanisms of ubiquitination in osteosarcoma;Frontiers in Oncology;2022-12-01
5. TIPE1 inhibits osteosarcoma tumorigenesis and progression by regulating PRMT1 mediated STAT3 arginine methylation;Cell Death & Disease;2022-09-23
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