Variation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors-Reference-Cited by-同舟云学术

Variation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors

Published:2017-12-15 Issue:4 Volume:122 Page:388-395
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Murray Michael¹,Zhang Wei V.¹,Edwards Robert J.²

Affiliation:

1. Pharmacogenomics and Drug Development Group, Discipline of Pharmacology; School of Medical Sciences; Sydney Medical School; University of Sydney; Sydney NSW Australia

2. Centre for Pharmacology and Therapeutics; Imperial College London; London UK

Funder

National Health and Medical Research Council

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12933/fullpdf

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3. Evidence from a population pharmacokinetics analysis for a major effect of CYP1A2 activity on inter- and intraindividual variations of clozapine clearance;Dailly;Prog Neuropsychopharmacol Biol Psychiatr,2002

4. Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test;Bertilsson;Br J Clin Pharmacol,1994

5. Cytochrome P450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing?;Dahl;Clin Pharmacokinet,2002

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