The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus-Reference-Cited by-同舟云学术

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The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus

Published:2018-03-13 Issue:1 Volume:123 Page:14-20
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Gao Fei¹,Gao Ying²,Meng Fangling¹,Yang Chunmei¹,Fu Jiangfeng¹,Li Yajun¹

Affiliation:

1. Department of Neurology; The First Affiliated Hospital of Xi'an Medical University; Xi'an China

2. Department of Radiotherapy Oncology; The First Affiliated Hospital of Medical College of Xi'an Jiaotong University; Xi'an China

Funder

The First Affiliated Hospital of Xi'an Medical University

Education Department of Shaanxi Province

Science and Technology Department of Shaanxi Provincial Government

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12973/fullpdf

Reference46 articles.

1. Drug-resistant epilepsy;Kwan;N Engl J Med,2011

2. Neuropathology of the blood-brain barrier and pharmaco-resistance in human epilepsy;Liu;Brain,2012

3. Drug resistance in brain diseases and the role of drug efflux transporters;Loscher;Nat Rev Neurosci,2005

4. The multidrug transporter hypothesis of drug resistance in epilepsy: proof-of-principle in a rat model of temporal lobe epilepsy;Brandt;Neurobiol Dis,2006

5. Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats;Vliet;Epilepsia,2006

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