Meningococcal Omp85 in Detergent-Extracted Outer Membrane Vesicle Vaccines Induces High Levels of Non-Functional Antibodies in Mice

Author:

Wedege E.1,Lie K.1,Bolstad K.1,Weynants V. E.2,Halstensen A.3,Herstad T. K.1,Kreutzberger J.4,Nome L.1,Naess L. M.1,Aase A.1

Affiliation:

1. Division of Infectious Disease Control; Department of Bacteriology and Immunology; Norwegian Institute of Public Health; Oslo; Norway

2. GSK Biologicals; Rixensart; Belgium

3. Institute of Medicine; University of Bergen; Bergen; Norway

4. Max Planck Institute for Molecular Genetics; Berlin; Germany

Publisher

Wiley

Subject

Immunology,General Medicine

Reference60 articles.

1. Production, characterization and control of a Neisseria meningitidis hexavalent class 1 outer membrane protein containing vesicle vaccine;Claassen;Vaccine,1996

2. Production, characterization and control of MenB-vaccine “Folkehelsa”: an outer membrane vesicle vaccine against group B meningococcal disease;Fredriksen;NIPH Ann,1991

3. The concept of “tailor-made”, protein-based, outer membrane vesicle vaccines against meningococcal disease;Holst;Vaccine,2005

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