Human antibody recognition of xenogeneic antigens (NeuGc and Gal) on porcine heart valves: could genetically modified pig heart valves reduce structural valve deterioration?-Reference-Cited by-同舟云学术

Human antibody recognition of xenogeneic antigens (NeuGc and Gal) on porcine heart valves: could genetically modified pig heart valves reduce structural valve deterioration?

Published:2016-08-11 Issue:5 Volume:23 Page:370-380
ISSN:0908-665X
Container-title:Xenotransplantation
language:en
Short-container-title:Xenotransplantation

Author:

Lee Whayoung¹,Long Cassandra¹,Ramsoondar Jagdeece²,Ayares David²,Cooper David K. C.¹,Manji Rizwan A.³⁴,Hara Hidetaka¹

Affiliation:

1. Thomas E. Starzl Transplantation Institute; University of Pittsburgh; Pittsburgh PA USA

2. Revivicor; Blacksburg VA USA

3. Department of Surgery; University of Manitoba; Winnipeg MB Canada

4. Cardiac Sciences Program; Winnipeg Regional Health Authority and St Boniface Hospital; Winnipeg MB Canada

Funder

National Institutes of Health

University of Pittsburgh

Revivicor, Inc.

Publisher

Wiley

Subject

Transplantation,Immunology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/xen.12254/fullpdf

Reference40 articles.

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2. Bioprosthetic heart valves: modes of failure;Siddiqui;Histopathology,2009

3. Bioprosthetic heart valves of the future;Manji;Xenotransplantation,2014

4. Very long-term survival implications of heart valve replacement with tissue versus mechanical prostheses in adults <60 years of age;Ruel;Circulation,2007

5. Accelerated degeneration of a bovine pericardial bioprosthetic aortic valve in children and young adults;Saleeb;Circulation,2014

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