Additive effect of radiosensitization by 2-deoxy-D-glucose delays DNA repair kinetics and suppresses cell proliferation in oral squamous cell carcinoma

Author:

Kawata Mayumi1,Ogi Kazuhiro1ORCID,Nishiyama Koyo1,Miyamoto Sho1,Nakagaki Takafumi1,Shimanishi Makoto1,Miyazaki Akihiro1,Hiratsuka Hiroyoshi1

Affiliation:

1. Department of Oral Surgery; School of Medicine; Sapporo Medical University; Sapporo Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Wiley

Subject

Periodontics,Cancer Research,Otorhinolaryngology,Oral Surgery,Pathology and Forensic Medicine

Reference21 articles.

1. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012;Ferlay;Int J Cancer,2015

2. Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology;Johnson;Periodontol,2000

3. Stromal features are predictive of disease mortality in oral cancer patients;Marsh;J Pathol,2011

4. Correlation of metabolism/hypoxia markers and fluorodeoxyglucose uptake in oral squamous cell carcinomas;Yamada;Oral Surg Oral Med Oral Pathol Oral Radiol,2012

5. Silencing of GLUT-1 inhibits sensitization of oral cancer cells to cisplatin during hypoxia;Shimanishi;J Oral Pathol Med,2013

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