Prior Running, as Well as Swimming, Hinders Swimming‐Based Taste Aversion Learning in Rats

Abstract

AbstractRunning in an exercise wheel or swimming in a water pool endows rats with a conditioned aversion to a taste substance consumed before the activity. The present study explores the psychophysiological processes underlying these activity‐based taste aversions. Experiment 1 demonstrated that prior experience of running or swimming (i.e., familiarization) hinders subsequent taste aversion learning based on swimming in rats, implying a similar psychophysiological process between running and swimming in establishing taste aversion. Experiment 2 replicated the findings of Experiment 1 with rats obtained from another animal supplier. The running‐to‐swimming cross‐familiarization effect demonstrated in these experiments contrasts with a previous report in which prior swimming had no effect on subsequent running‐based taste aversion learning. Theoretical considerations regarding such asymmetrical cross‐familiarization effects extended to discussions on the similarities and differences in the psychophysiological states induced by running, swimming, and emetic lithium chloride injection.