Genetic and Nongenetic Factors Affecting Clopidogrel Response in the Egyptian Population

Author:

Khalil BM1,Shahin MH2,Solayman MHM23,Langaee T2,Schaalan MF14,Gong Y2,Hammad LN1,Al‐Mesallamy HO5,Hamdy NM5,El‐Hammady WA6,Johnson JA27

Affiliation:

1. Department of Biochemistry, Faculty of Pharmacy Misr International University Cairo Egypt

2. Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, College of Pharmacy University of Florida Gainesville Florida USA

3. Department of Clinical Pharmacy, Faculty of Pharmacy Ain Shams University Cairo Egypt

4. Department of Pharmacy Practice and Clinical Pharmacy Misr International University Cairo Egypt

5. Department of Biochemistry, Faculty of Pharmacy Ain Shams University Cairo Egypt

6. Department of Cardiology, Faculty of Medicine Ain Shams University Cairo Egypt

7. Division of Cardiovascular Medicine, Department of Medicine University of Florida Gainesville Florida USA

Funder

Misr International University, Cairo, Egypt and the University of Florida, Center of Pharmacogenomics and NIH

IGNITE Network

American Heart Association predoctoral fellowship

Embassy of the Arab Republic of Egypt

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference41 articles.

1. Dual antiplatelet therapy with clopidogrel and aspirin after carotid artery stenting;Bhatt D.L.;J. Invasive Cardiol.,2001

2. A high maintenance dose of clopidogrel improves short‐term clinical outcomes in patients with acute coronary syndrome undergoing drug‐eluting stent implantation;Han Y.L.;Chin. Med. J. (Engl).,2009

3. Variability in platelet responsiveness to clopidogrel among 544 individuals

4. Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update

5. Variability in Individual Responsiveness to Clopidogrel

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