Pharmacokinetic interactions among imatinib, bosentan and sildenafil, and their clinical implications in severe pulmonary arterial hypertension
Author:
Affiliation:
1. Novartis Pharma AG; Basel Switzerland
2. Novartis Horsham Research Centre; Horsham West Sussex UK
3. Novartis Pharmaceuticals; East Hanover USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12584/fullpdf
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2. Imatinib mesylate has the potential to exert its efficacy by down-regulating the plasma concentration of platelet-derived growth factor in patients with pulmonary arterial hypertension;Hatano;Int Heart J,2010
3. Early detection and management of pulmonary arterial hypertension;Humbert;Eur Respir Rev,2012
4. Imatinib mesylate for the treatment of pulmonary arterial hypertension;Ten;Expert Opin Investig Drugs,2012
5. Advances in diagnosis and treatment in patients with pulmonary arterial hypertension;Park;Catheter Cardiovasc Interv,2008
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