Physiologically based pharmacokinetic model for 6-mercpatopurine: exploring the role of genetic polymorphism in TPMT enzyme activity
Author:
Affiliation:
1. Centre for Applied Pharmacokinetics Research, Manchester Pharmacy School; The University of Manchester; Oxford Road Manchester M13 9PT United Kingdom
Funder
ERA-NET Priority Medicines for Children (PRIOMEDCHILD)
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12588/fullpdf
Reference48 articles.
1. Pharmacokinetics and metabolism of thiopurines in children with acute lymphoblastic leukemia receiving 6-thioguanine versus 6-mercaptopurine;Erb;Cancer Chemother Pharmacol,1998
2. The clinical pharmacology of 6-mercaptopurine;Lennard;Eur J Clin Pharmacol,1992
3. Pharmacokinetics of oral 6-mercaptopurine - relationship between plasma levels and urine excretion of parent drug;Endresen;Ther Drug Monit,1990
4. Treating childhood acute lymphoblastic leukemia without cranial irradiation;Pui;N Engl J Med,2009
5. Variable bioavailability of oral mercaptopurine. Is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered?;Zimm;N Engl J Med,1983
Cited by 20 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy;Biochemical Pharmacology;2024-08
2. The Effect of Renal Replacement Therapy in a Patient with Mercaptopurine Toxicity: Time to Revise Guidelines;Current Drug Safety;2024-05
3. Genotype influenced pharmacokinetics of anticancer medicine: A connecting link;Biomarkers in Cancer Detection and Monitoring of Therapeutics;2024
4. Genome-Wide Association Study for the Genetic Determinants of Thiopurine Methyltransferase Protein Expression in Human Livers and Racial Differences;Pharmaceutical Research;2023-07-10
5. Bioequivalence of Two 6‐Mercaptopurine Tablet Formulations in Healthy Fasting Chinese Volunteers;Clinical Pharmacology in Drug Development;2023-07-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3