The pan‐cancer mutational landscape of the PPAR pathway reveals universal patterns of dysregulated metabolism and interactions with tumor immunity and hypoxia

Author:

Chang Wai Hoong1,Lai Alvina G.1

Affiliation:

1. Nuffield Department of MedicineUniversity of Oxford Oxford United Kingdom

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference64 articles.

1. Pan-cancer genomic amplifications underlie a WNT hyperactivation phenotype associated with stem cell-like features leading to poor prognosis

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4. An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK‐STAT signaling components;Chang W.H.;bioRxiv,2019

5. Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with hypoxia and immunoevasion;Chang W.H.;bioRxiv,2019

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