Hypertrophic cardiomyopathy associated E22K mutation in myosin regulatory light chain decreases calcium‐activated tension and stiffness and reduces myofilament Ca 2+ sensitivity
Author:
Affiliation:
1. School of Nursing Medical College Soochow University Suzhou China
2. Department of Molecular and Cellular Pharmacology University of Miami FL USA
3. Department of Anatomy and Cell Biology University of Iowa IA USA
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.15753
Reference56 articles.
1. Prevalence of Hypertrophic Cardiomyopathy in a General Population of Young Adults
2. New Perspectives on the Prevalence of Hypertrophic Cardiomyopathy
3. Genetic Basis of Hypertrophic Cardiomyopathy: From Bench to the Clinics
4. Hereditary heart disease: pathophysiology, clinical presentation, and animal models of HCM, RCM, and DCM associated with mutations in cardiac myosin light chains
5. Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle
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