Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation

Author:

Polasek Thomas M.12ORCID,Tucker Geoffrey T.3,Sorich Michael J.14,Wiese Michael D.5,Mohan Titus6,Rostami-Hodjegan Amin78,Korprasertthaworn Porntipa9,Perera Vidya10ORCID,Rowland Andrew14ORCID

Affiliation:

1. Department of Clinical Pharmacology; Flinders University; Adelaide SA Australia

2. d3 Medicine; A Certara Company; Melbourne VIC Australia

3. Medicine and Biomedical Sciences (Emeritus); University of Sheffield; Sheffield UK

4. Flinders Centre for Innovation in Cancer; Flinders University; Adelaide SA Australia

5. School of Pharmacy and Medical Sciences; University of South Australia; Adelaide SA Australia

6. Department of Psychiatry; Flinders Medical Centre; Adelaide SA Australia

7. Certara, Blades Enterprise Centre; Sheffield UK

8. Centre for Applied Pharmacokinetic Research; University of Manchester; Manchester UK

9. Department of Pharmacology, Faculty of Science; Mahidol University; Bangkok Thailand

10. Clinical Pharmacology and Pharmacometrics, Early Clinical and Translational Research; Bristol Myers Squibb; Princeton NJ USA

Funder

Simcyp Ltd, A Certara Company, Sheffield, UK

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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