Effects of ageing and senescence on pancreatic β-cell function-Reference-Cited by-同舟云学术

Effects of ageing and senescence on pancreatic β-cell function

Published:2016-09 Issue: Volume:18 Page:58-62
ISSN:1462-8902
Container-title:Diabetes, Obesity and Metabolism
language:en
Short-container-title:Diabetes Obes Metab

Author:

Helman A.¹,Avrahami D.¹²,Klochendler A.¹,Glaser B.²,Kaestner K. H.³,Ben-Porath I.¹,Dor Y.¹

Affiliation:

1. Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada; The Hebrew University-Hadassah Medical School; Jerusalem Israel

2. Endocrinology and Metabolism Service, Department of Internal Medicine; Hadassah-Hebrew University Medical Center; Jerusalem Israel

3. Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine; University of Pennsylvania; Philadelphia Pennsylvania

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.12719/fullpdf

Reference28 articles.

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2. Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans;Meier;Diabetes,2008

3. Significant human {beta}-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating;Perl;J Clin Endocrinol Metab,2010

4. Very slow turnover of beta-cells in aged adult mice;Teta;Diabetes,2005

5. Adaptive beta-cell proliferation is severely restricted with advanced age;Rankin;Diabetes,2009

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