Inhibition of HSP90 and Activation of HSF1 Diminish Macrophage NLRP3 Inflammasome Activity in Alcohol‐Associated Liver Injury-Reference-Cited by-同舟云学术

Inhibition of HSP90 and Activation of HSF1 Diminish Macrophage NLRP3 Inflammasome Activity in Alcohol‐Associated Liver Injury

Published:2020-05-18 Issue:6 Volume:44 Page:1300-1311
ISSN:0145-6008
Container-title:Alcoholism: Clinical and Experimental Research
language:en
Short-container-title:Alcohol Clin Exp Res

Author:

Choudhury Asmita¹,Bullock Daniel¹,Lim Arlene¹,Argemi Josepmaria²,Orning Pontus³⁴,Lien Egil³⁴,Bataller Ramon²,Mandrekar Pranoti¹^ORCID

Affiliation:

1. From the Department of Medicine (AC, DB, AL, PM) University of Massachusetts Medical School Worcester Massachusetts

2. Division of Gastroenterology, Hepatology and Nutrition (JA, RB) Pittsburgh Liver Research Center University of Pittsburgh Medical Center Pittsburgh Pennsylvania

3. Program in Innate Immunity (PO, EL) Division of Infectious Diseases and Immunology Department of Medicine University of Massachusetts Medical School Worcester Massachusetts

4. Department of Clinical and Molecular Medicine (PO, EL) Centre of Molecular Inflammation Research NTNU Trondheim Norway

Funder

National Institute of Alcohol Abuse and Alcoholism

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acer.14338

Reference32 articles.

1. NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

2. Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury