Defining extended half-life rFVIII-A critical review of the evidence

Author:

Mahlangu J.1ORCID,Young G.2ORCID,Hermans C.3ORCID,Blanchette V.4,Berntorp E.5,Santagostino E.6

Affiliation:

1. Faculty of Health Sciences; University of the Witwatersrand and National Health Laboratory Service; Charlotte Maxeke Johannesburg Academic Hospital; Johannesburg South Africa

2. Children's Hospital Los Angeles; University of Southern California Keck School of Medicine; Los Angeles CA USA

3. Haemostasis and Thrombosis Unit; Division of Haematology; Cliniques universitaires Saint-Luc; Brussels Belgium

4. Pediatric Thrombosis and Hemostasis Program; Division of Hematology/Oncology; Hospital for Sick Children; University of Toronto; Toronto ON Canada

5. Centre for Thrombosis and Haemostasis; Lund University; Malmö Sweden

6. A. Bianchi Bonomi Hemophilia and Thrombosis Center; IRCCS Ca' Granda Foundation; Maggiore Hospital Policlinico of Milan; Milan Italy

Publisher

Wiley

Subject

Genetics (clinical),Hematology,General Medicine

Reference65 articles.

1. Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B;Nilsson;J Intern Med,1992

2. Joint outcomes in patients with haemophilia: the importance of adherence to preventive regimens;Berntorp;Haemophilia,2009

3. Baxter Healthcare Corporation ADVATE, prescribing information [Antihemophilic factor (recombinant), plasma/albumin-free method] http://www.fda.gov/downloads/BloodBloodProducts/ucm059095.pdf

4. When should prophylactic treatment in patients with haemophilia A and B start? - The German experience;Kreuz;Haemophilia,1998

5. Half-life extended factor VIII for the treatment of hemophilia A;Tiede;J Thromb Haemost,2015

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