No indication of increased infection rates using low-dose alemtuzumab instead of anti-thymocyte globulin as graft-versus-host disease prophylaxis before allogeneic stem cell transplantation

Author:

Neumann Thomas1ORCID,Schneidewind Laila1,Thiele Thomas2,Pink Daniel3,Schulze Meike4,Schmidt Christian1,Krüger William1

Affiliation:

1. Department of Haematology, Oncology, Transplantation; University Medical Centre; Ernst-Moritz-Arndt University; Greifswald Germany

2. Institute of Immunology and Transfusion Medicine; University Medical Centre; Ernst-Moritz-Arndt University; Greifswald Germany

3. Department of Haematology, Oncology; HELIOS Klinikum Bad Saarow; Bad Saarow Germany

4. Department of Internal Medicine; Wolgast Hospital; Wolgast Germany

Publisher

Wiley

Subject

Infectious Diseases,Transplantation

Reference37 articles.

1. Anti-human thymocyte globulin (ATG) for prophylaxis and treatment of graft-versus-host disease in recipients of allogeneic marrow grafts;Weiden;Transplant Proc,1978

2. A randomized study of the prevention of acute graft-versus-host disease;Ramsay;N Engl J Med,1982

3. Polyclonal anti-thymocyte globulins for the prophylaxis of graft-versus-host disease after allogeneic stem cell or bone marrow transplantation in adults;Theurich;Cochrane Database Syst Rev,2012

4. Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: A randomised, open-label, multicentre phase 3 trial;Finke;Lancet Oncol,2009

5. CAMPATH: From concept to clinic;Waldmann;Philos Trans R Soc Lond B Biol Sci,2005

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