Influence of thiopurine S‐methyltransferase polymorphisms in mercaptopurine pharmacokinetics in healthy volunteers-Reference-Cited by-同舟云学术

Influence of thiopurine S‐methyltransferase polymorphisms in mercaptopurine pharmacokinetics in healthy volunteers

Published:2018-11-15 Issue:4 Volume:124 Page:449-455
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Saiz‐Rodríguez Miriam¹,Ochoa Dolores¹²,Belmonte Carmen¹²,Román Manuel¹²,Martínez‐Ingelmo Cristina¹,Ortega‐Ruíz Lucía¹,Sarmiento‐Iglesias Carmen¹,Herrador Coral¹,Abad‐Santos Francisco¹²³

Affiliation:

1. Clinical Pharmacology Department Instituto Teófilo Hernando Instituto de Investigación Sanitaria La Princesa (IP) Universidad Autónoma de Madrid (UAM) Hospital Universitario de La Princesa Madrid Spain

2. UICEC Hospital Universitario de La Princesa Plataforma SCReN (Spanish Clinical Research Network) Instituto de Investigación Sanitaria La Princesa (IP) Madrid Spain

3. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) Instituto de Salud Carlos III Madrid Spain

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcpt.13153

Reference18 articles.

1. Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond

2. U.S. Food & Drug Administration (FDA).Label information for mercaptopurine.https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/009053s032lbl.pdf. Accessed August 14 2018.

3. Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status

4. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

5. Interindividual variability in TPMT enzyme activity: 10 years of experience with thiopurine pharmacogenetics and therapeutic drug monitoring

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