Enhanced high-mobility group box 1 (HMGB1) modulates regulatory T cells (Treg)/T helper 17 (Th17) balance via toll-like receptor (TLR)-4-interleukin (IL)-6 pathway in patients with chronic hepatitis B

Author:

Li J.1,Wang F.-P.2,She W.-M.2,Yang C.-Q.1,Li L.2,Tu C.-T.2,Wang J.-Y.2,Jiang W.2

Affiliation:

1. Department of Gastroenterology; Tongji Hospital; Tongji University; Shanghai China

2. Department of Gastroenterology; Zhongshan Hospital; Fudan University; Shanghai China

Funder

National Nature Science Foundation of China

Nature Science Foundation of Shanghai

Publisher

Wiley

Subject

Virology,Infectious Diseases,Hepatology

Reference35 articles.

1. Hepatitis B virus infection-natural history and clinical consequences;Ganem;N Engl J Med,2004

2. The natural history of chronic hepatitis B;Lai;J Viral Hepat,2007

3. Management of hepatitis B in China;Lu;Chin Med J (Engl),2009

4. Host immunity influences disease progression and antiviral efficacy in humans infected with hepatitis B virus;Wang;Expert Rev Gastroenterol Hepatol,2009

5. Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection;Bertoletti;Gut,2012

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