Pharmacokinetics and pharmacodynamics of intravenous continuous rate infusion and repeated intramuscular administration of dexmedetomidine in standing horses

Author:

Shane Sarah E.1ORCID,Langston Vernon C.1ORCID,Wills Robert W.2ORCID,Denney William S.3ORCID,Knych Heather4ORCID,Fontenot Robin L.5ORCID,Meyer Robert E.1,Natalini Claudio C.1ORCID

Affiliation:

1. Department of Clinical Sciences College of Veterinary Medicine Mississippi State University Mississippi State MS USA

2. Department of Basic Sciences College of Veterinary Medicine Mississippi State University Mississippi State MS USA

3. Human Predictions, LLC Boston MA USA

4. Department of Molecular Biosciences School of Veterinary Medicine University of California Davis CA USA

5. Department of Pathobiology and Population Medicine College of Veterinary Medicine Mississippi State University Mississippi State MS USA

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Reference29 articles.

1. Pharmacokinetics of medetomidine in ponies and elaboration of a medetomidine infusion regime which provides a constant level of sedation

2. Cardiopulmonary effects and pharmacokinetics of i.v. dexmedetomidine in ponies

3. Blode H. Brett M. Bührens K. G. Cawello W. Frick A. Gieschke R. Giese U. Heine P. R. Kloft C. Kovar A. Pabst G. Pechstein B. Römer A. Steinsträer A. Terlinden R. Weimann H. J. Würthwein G. &Zimmermann H.(2004).Collection of terms symbols equations and explanations of common pharmacokinetic and pharmacodynamic parameters and some statistical functions.1–23.

4. Simple, automatic noncompartmental analysis: The PKNCA R package;Buckeridge C.;Journal of Pharmacokinetics and Pharmacodynamics,2015

5. Denney W. S.(2020).Pk.calc.mrt. PKNCA v0.9.4. Retrieved from:https://www.rdocumentation.org/packages/PKNCA/versions/0.9.4/topics/pk.calc.mrt

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