HLA antibody repertoire in infants suggests selectivity in transplacental crossing

Author:

Savulescu Dana M.1ORCID,Groome Michelle23,Malfeld Susan C. K.1,Madhi Shabir23,Koen Anthonet23,Jones Stephanie23,Duxbury Vania4,Scheuermaier Karine4,De Assis Rosa Debbie5,Suchard Melinda16

Affiliation:

1. Centre for Vaccines and Immunology (CVI) National Institute for Communicable Diseases (NICD)A Division of the National Health Laboratory Service Johannesburg Gauteng South Africa

2. Medical Research Council: Respiratory and Meningeal Pathogens Research Unit Faculty of Health Sciences University of the Witwatersrand Johannesburg Gauteng South Africa

3. Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases Faculty of Health Sciences University of the Witwatersrand Johannesburg Gauteng South Africa

4. Brain Function Research Group School of Physiology Faculty of Health Sciences University of the Witwatersrand Johannesburg Gauteng South Africa

5. School of Molecular and Cell Biology Faculty of Science University of the Witwatersrand Johannesburg Gauteng South Africa

6. Department of Chemical Pathology Faculty of Health Sciences University of the Witwatersrand Johannesburg Gauteng South Africa

Publisher

Wiley

Subject

Obstetrics and Gynaecology,Reproductive Medicine,Immunology,Immunology and Allergy,Obstetrics and Gynaecology,Immunology

Reference74 articles.

1. BuchlaE dePillisLG RadunskayaAE.A brief background on the immune system.https://www.researchgate.net/publication/239744614_A_Brief_Background_on_the_Immune_System. 2002

2. Existence of an immunoglobulin G component of naturally occurring HLA class I antibodies that are not directed against self-antigens in human serum

3. “Natural” Human Leukocyte Antigen Antibodies Found in Nonalloimmunized Healthy Males

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