Affiliation:
1. King Faisal Specialist Hospital & Research Centre, Pharmacy Department, Riyadh, Saudi Arabia
Abstract
Abstract
Objectives
To identify the intravenous (IV) medications that are prepared in glass bottles at the institution and establish which of these medications can be prepared in flexible IV bags such as polyvinyl chloride (PVC) or non-PVC instead of glass bottles. The cost implication of switching from glass bottles to flexible IV bags was calculated.
Methods
A study using FOCUS-PDCA model to identify IV medications prepared in glass bottles and establish which of these medications could be prepared in IV bags (PVC or non-PVC). The cost impact of switching from glass bottles to IV plastic bags (including PVC or non-PVC) was calculated. The stability data obtained were used as a reference for updating pharmacy internal IV preparation charts.
Key findings
A total of 17 IV medications were found to be prepared in IV glass bottles. Of these 17 medications, only 8 (47%) were prepared in IV glass bottles due to incompatibility with PVC bags. For 7 (41%) of the medications, of which 6 were monoclonal antibodies (MABs), the reason for preparation in glass bottles was unclear as these medications are compatible with either PVC or non-PVC or both. The potential cost savings associated with switching all of the identified medications to IV plastic bags (either non-PVC or PVC) exceeded $200 000.
Conclusions
The elimination of glass bottles within the institution resulted in a significant cost saving. The use of FOCUS-PDCA model can help healthcare institution achieve significant improvements in process and realize significant cost savings.
Publisher
Oxford University Press (OUP)
Subject
Public Health, Environmental and Occupational Health,Health Policy,Pharmaceutical Science,Pharmacy
Reference65 articles.
1. ASHP guidelines on quality assurance for pharmacy-prepared sterile products. American Society of Health-System Pharmacists,2000
2. Pharmaceutical compounding—sterile preparations (general information);United States Pharmacopeia,2013
3. ASHP guidelines on compounding sterile preparations;Am J Health Syst Pharm,2014
4. Compatibility of nitroglycerin, diazepam and chlorpromazine with a new multilayer material for infusion containers;Kambia;J Pharm Biomed Anal,2005
5. Investigation of the release behavior of diethylhexyl phthalate from polyvinyl-chloride tubing for intravenous administration;Hanawa;Int J Pharm,2000
Cited by
10 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献